2094 Etiology and Clinical Feature of Oral Allergy Syndrome in Children

Thursday, 15 October 2015
Hall D1 Foyer (Floor 3) (Coex Convention Center)

Young a Park, MD , Department of Pediatrics and Institute of Allergy, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea

Kyunguk Jeong, MD , Department of Pediatrics, Ajou University School of Medicine, Suwon, South Korea

Yoon Hee Kim, MD , Department of Pediatrics and Institute of Allergy, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea

In Suk Sol, MD , Department of Pediatrics and Institute of Allergy, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea

Seo Hee Yoon, MD, PhD , Department of Pediatrics and Institute of Allergy, Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, South Korea

Kyung Won Kim, MD, PhD , Department of Pediatrics and Institute of Allergy, Yonsei University College of Medicine, Seoul, South Korea

Myung Hyun Sohn, MD, PhD , Department of Pediatrics and Institute of Allergy, Yonsei University College of Medicine, Seoul, South Korea

Sooyoung Lee, MD, PhD , Department of Pediatrics, Ajou University School of Medicine, Suwon, South Korea

Kyu-Earn Kim, MD, PhD , Department of Pediatrics and Institute of Allergy, Yonsei University College of Medicine, Seoul, South Korea

Background: Oral allergy syndrome (OAS) is defined as the symptoms of IgE-mediated immediate allergy localized in the oral mucosa, and the characteristics depend on the lability of the antigen. OAS is regarded as uncommon manifestations of pediatric population. This study focused on the allergenic relationship between pollen and food allergen of oral allergy syndrome in Korean children.

Methods: The study was based on a data analysis of patients, who were diagnosed with oral allergy syndrome at Ajou University hospital, Severance children’s hospital, Kangnam severance hospital from January 2008 to December 2014. Clinical details were collected by medical history and telephone survey.

Results: The subjects were 59 male and 38 female with median aged 9 years. In 97 children with oral allergy syndrome, most common causative food of allergy syndrome was apple. Pollen with the highest rate of positive responses is birch. In children with oral allergy syndrome, children sensitized birch have high risk of reaction to apple. The youngest patient with oral allergy syndrome is 3 years old girl. 65 children had reaction to more than 2 foods.

Conclusion: oral allergy syndrome may commonly affect children who are allergic to pollen. For children with oral allergy syndrome, knowledge of specific sensitization patterns has consequences for dietary management.