Mariana Stoll Leão
,
Allergy and Immunology, Instituto Nacional De Saude Da Mulher, Da Criança e Do Adolescente Fernandes Figueira - IFF/ Fiocruz, Rio de Janeiro, Brazil
Ana Luiza Cotta De Alencar Araripe
,
Dermatology, Instituto Nacional De Saude Da Mulher, Da Criança e Do Adolescente Fernandes Figueira - IFF/ Fiocruz, Rio de Janeiro, Brazil
Elisa Fontenelle Oliveira
,
Dermatology, Instituto Nacional De Saude Da Mulher, Da Criança e Do Adolescente Fernandes Figueira - IFF/ Fiocruz, Rio de Janeiro, Brazil
Luana Pires Helal
,
Allergy and Immunology, Instituto Nacional De Saude Da Mulher, Da Criança e Do Adolescente Fernandes Figueira - IFF/ Fiocruz, Rio de Janeiro, Brazil
Ana Rizia Agra Castro
,
Allergy and Immunology, Instituto Nacional De Saude Da Mulher, Da Criança e Do Adolescente Fernandes Figueira - IFF/ Fiocruz, Rio de Janeiro, Brazil
Liziane Nunes
,
Allergy and Immunology, Instituto Nacional De Saude Da Mulher, Da Criança e Do Adolescente Fernandes Figueira - IFF/ Fiocruz, Rio de Janeiro, Brazil
Paula Lauria
,
Allergy and Immunology, Instituto Nacional De Saude Da Mulher, Da Criança e Do Adolescente Fernandes Figueira - IFF/ Fiocruz, Rio de Janeiro, Brazil
Abelardo Neto
,
Allergy and Immunology, Instituto Nacional De Saude Da Mulher, Da Criança e Do Adolescente Fernandes Figueira - IFF/ Fiocruz, Rio de Janeiro, Brazil
Flavia Anisio
,
Allergy and Immunology, Instituto Nacional De Saude Da Mulher, Da Criança e Do Adolescente Fernandes Figueira - IFF/ Fiocruz, Rio de Janeiro, Brazil
Celso Ungier
,
Allergy and Immunology, Instituto Nacional De Saude Da Mulher, Da Criança e Do Adolescente Fernandes Figueira - IFF/ Fiocruz, Rio de Janeiro, Brazil
Sandra Bastos
,
Allergy and Immunology, Instituto Nacional De Saude Da Mulher, Da Criança e Do Adolescente Fernandes Figueira - IFF/ Fiocruz, Rio de Janeiro, Brazil
Background: Acute generalized exanthematous pustulosis (AGEP) is a rare and severe subtype of drug eruption, characterized by acute, extensive, non-folicular, sterile pustules overlying an erythematous skin, associated with fever and leukocytosis.
Methods: Case report of a 6-year-old female child with encephalopathy and chronic lung disease, who was treated with intravenous antibiotics, antipyretic and antiepiletics during hospitalization for sepsis. She evolved with diffuse erythemata and non follicular pustules on her trunk, flexural areas, palms and soles.
Results: The drug history, clinical presentation, cutaneous histopathological findings (subcorneal pustular dermatitis) and the prompt regression of the lesions after withdrawal of the suspected drugs were consistent to ratify the diagnosis of AGEP.
Conclusions: AGEP is an uncommon reaction , usually seen after drug exposure and clinicians should keep in mind the possibility of this skin eruption.
