Study Design: Individual cohort study
Methods: We analyzed data from Snoring Child Cohort of 208 children. The data encompassed questionnaire about chronic rhinitis, and the result of skin prick test (SPT) for 5 inhalent and specific IgE for 2 allergens. Children were classified into four groups, namely allergic rhinitis (rhinitis plus positive SPT), nonallergic rhinitis (rhinitis plus negative SPT), sensitization only (no rhinitis plus positive SPT), and control (no rhinitis plus negative SPT).
Results: Finally, the data of 124 children were analyzed. Among 18 children with allergic rhinitis at 7 year, 13 (72.2%) became sensitization only after 2 years and only 5 (27.8%) were remained as allergic rhinitis. Five (26.3%) out of 19 with children nonallergic rhinitis at 7 year turned into allergic rhinitis at 9 year and 7 (36.8%) into control. Twenty six (86.7%) out of 30 children with sensitization only at 7 year were remained as same at 9 year. Among 59 control children at 7 year, 2 (3.3%) became those with allergic rhinitis, 7 (11.9%) with nonallergic rhinitis, and 16 (27.1%) with sensitization only at 9 year.
Conclusion: The status of chronic rhinitis and allergen sensitization is very changeable in children.