Presentation: Burden and Correlates of Cigarette Smoking and Respiratory Airway Obstruction: An Observation in Urban Adult Population of West Bengal (India) ( World Allergy Congress)

Friday, 16 October 2015

Hall D1 Foyer (Floor 3) (Coex Convention Center)

Kaushik Chakraborty, MPS, MSW, MBA , Population Health, Barrackpore Population Health Research Foundation, Kolkata, India

Tanmay Mahapatra , Public Health, Mission Arogya Health and Information Technology Research Foundation, India

Nilanjana Chakraborty , Population Health, Barrackpore Population Health Research Foundation, India, India

Ramendra Nath Mitra , School of Population Health, Sir Charles Gairdner Hospital (University of Western Australia), Australia

Peter L Thompson , School of Population Health, Sir Charles Gairdner Hospital (University of Western Australia), Australia

Arthur William Musk , School of Population Health, School of Population Health, University of Western Australia, Australia

Background:

Cigarette smoking is the predominate risk factor for developing chronic airway obstruction. Globally COPD is one of the leading causes of mortality and morbidity. The purpose of the study was to assess the burden and correlation of cigarette smoking and respiratory airway obstruction among healthy adults.

Methods:

The cross-sectional study included 2572 healthy adult without any respiratory illness and non communicable diseases. Smoking and other information were collected using a standardized questionnaire. Lung function test was performed by spirometer and cutoff point derived from GOLD guideline. Multivariate logistic regression analysis was performed.

Results:

1034 (40.20%) were male and 1538 (59.80%) female. 304 (11.82%) were currently heavy Smokers, among them two were female. Male smokers 421 (40.71%) and female 4 (0.26%). Overall airway obstruction was 646 (25.12%), 297 (28.72%) were male and 349 (22.69%) female.

Compare to never smokers, former smokers [OR=1.75, 95% CI: 1.15, 2.68, p=0.0096] and current heavy smokers [OR=2.01, 95% CI: 1.49, 2.69, p<0.001] were associated with obstruction. Increasing age was associated with increasing obstruction [OR=1.05, 95% CI: 1.04, 1.06, p<.0001]. Obstruction was associated with shortness of breath [OR=1.31, 95% CI: 1.03, 1.65, p=0.0245], cough [OR=1.83, 95% CI: 1.20, 2.80, p=0.0049], phlegm [OR=2.38, 95% CI: 1.53, 3.68, p=.0001], wheezing [OR=3.70, 95% CI: 2.00, 6.85, p<.0001] compare to no obstruction. Smokers with obstruction were associated with phlegm [OR=2.40, 95% CI: 1.09, 5.27, p=0.0294], wheezing [OR=9.61, 95% CI: 2.08, 44.45, p=0.0038] reference to smokers without obstruction. Among no obstruction SOB [OR=1.87, 95% CI: 1.15, 3.08, p=0.0114] and phlegm [OR=2.65, 95% CI: 1.07, 6.57, p=0.0352] were associated with smokers reference to non-smokers.

Conclusion:

One in four or one quarter of the apparent healthy adults of the cohort suffered from undiagnosed airway obstruction. Association had been documented between cigarette smoking and the development of airway obstruction and symptoms.

3074 Burden and Correlates of Cigarette Smoking and Respiratory Airway Obstruction: An Observation in Urban Adult Population of West Bengal (India)