Thursday, 15 October 2015
Hall D1 Foyer (Floor 3) (Coex Convention Center)
Han Seok Cho
,
Childhood Asthma Atopy Center, Department of Pediatrics, Asan Medical Center, Seoul, South Korea
Min-Ju Kim
,
Childhood Asthma Atopy Center, Department of Pediatrics, Asan Medical Center, Seoul, South Korea
Keum Hee Hwang
,
Childhood Asthma Atopy Center, Department of Pediatrics, Asan Mecical Center, Seoul, South Korea
Min Ji Kim
,
Childhood Asthma Atopy Center, Department of Pediatrics, Asan Medical Center, Seoul, South Korea
Young Ok Park
,
Childhood Asthma Atopy Center, Department of Pediatrics, Asan Medical Center, Seoul, South Korea
Hye Yeong Lee
,
Department of Children’s Hospital Nursing, Asan Medical Center, Seoul, South Korea
Hee Seong Kim
,
Department of Children’s Hospital Nursing, Asan Medical Center, Seoul, South Korea
Eun Lee, MD
,
Department of Pediatrics, Univer, Asan Medical Center, Seoul, South Korea
Hyun-Ju Cho, MD
,
Department of Pediatrics, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea
Jinho Yu, MD, PhD
,
Department of Pediatrics, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea
Soo-Jong Hong, MD, PhD
,
Department of Pediatrics, Childhood Asthma Atopy Center, Enviromental Health Center, University of Ulsan College of Medicine,, Asan Medical Center, Seoul, South Korea
Gelatin allergy has been well described in type 1 hypersensitivity reactions to vaccines, but only a few case reports have been published about anaphylaxis associated with food.
We report a 5 years old boy that developed anaphylaxis after eating gummy bears. He was referred for evaluation after 2 episodes of anaphylaxis after ingestion of gummy products. The first episode occurred within 10 minutes of consuming more than 1 package of Haribo Gold Bear Candy with development of diffuse urticaria and generalized rash, angioedema, and pruritus with wheezing. Approximately 2 months later, a second episode occurred after ingesting Mygummy fruit snack 1 package. Ten minutes after ingestion, he had generalized urticaria and erythema, which resolved after receiving antihistamine.
Prick to prick skin testing of gelatin-containing gums (Haribo and Mygummy) soaked in water and porcine gelatin were positive reactions. And additional intradermal testing with a 1:100 gelatin was strongly reactive. ImmunoCAP testing showed an increasd IgE level to bovine gelatin, at 4.50 kUA/L(Porcine gelatin in not available in Korea. Mammalian gelatins are well known that there is cross-reactivity).
Double-blind, placebo-controlled food challenge is the gold standard for the diagnosis of food allergy. However,this was not conducted in this patient, because he had already
had several reactions to foods that contained gelatin, including anaphylactic reactions, and he had evidence of specific IgE to gelatin, skin testing and intradermal test.
The patent was advised to avoid all gelatin-containing food, medications, and vaccines.
