Background : Although anaphylaxis is recognized as an important life-threatening condition, data are limited regarding its characteristics in the Korean children
Objective : We sought to estimate the triggers of anaphylaxis by age groups in Korean children
Methods : A retrospective medical record review was performed on children patients diagnosed with anaphylaxis between 2009 and 2013 in 23 tertiary hospitals of South Korea
Results : A total 991 cases (66% male, mean age 5.89±5,24) were reported, with 36.6% below 2 years of age. Food was the most common cause (74.7%), followed by drugs and radiocontrast media (10.7%), idiopathic (9.2%), and exercise (3.6%). The most common offending food allergen was milk, followed by egg white, walnut, wheat, buckwheat, and peanut. Milk was the most common trigger of anaphylaxis in young children. In older children, seafood was the most common trigger of anaphylaxis. The rate of drugs in triggers of anaphylaxis was increased by age.
Conclusion : Food was the commonest trigger of anaphylaxis in Korean children. The common triggers of food induced anaphylaxis have changed over time in Korean children.