Objective : We sought to investigate the clinical features of anaphylaxis in Korean children.
Methods : A retrospective medical record review was performed on children patients diagnosed with anaphylaxis between 2009 and 2013 in 23 tertiary hospitals of South Korea
Results : A total 991 cases (66% male, mean age 5.89±5,24) were reported, with 36.6% below 2 years of age. The most common past medical history was food allergy. A previous reaction to the same allergen was reported by 23.1%. Cutaneous symptoms (96.1%) were the most common symptoms followed by respiratory (85.0%), gastrointestinal (26.6%), neurologic (15.5%), and cardiovascular (14.3%). Although, cardiovascular symptoms of anaphylaxis were rare in young children (7.7%), cardiovascular symptoms were increased with age. Cardiovascular symptoms were common in reactions caused by insect sting(50.0%). The mainstay of first-line treatment in hospital included antihistamine (61.2%), corticosteroids (42.2%) and epinephrine(34.0%). Epinephrine auto-injectors were prescribed for 26.6%.
Conclusion : We identified differences in the symptoms of anaphylaxis according to age and triggers. Rate of use of epinephrine as the first-aid medication is too low, and prescription rate of adrenalin auto-injector is too low regardless of age of patients.