2099 Clinical Characteristics of Anaphylaxis in Korean Children

Thursday, 15 October 2015
Hall D1 Foyer (Floor 3) (Coex Convention Center)

Taek-Ki Min, MD, PhD , Pediatrics, Soonchunhyang University College of Medicine, Seoul, South Korea

Kangmo Ahn, MD, PhD , Department of Pediatrics, Samsung Medical Center, Seoul, South Korea

Jihyun Kim, MD , Department of Pediatrics, Samsung Medical Center, Seoul, South Korea

So-Yeon Lee, MD , Department of Pediatrics, Hallym University Sacred Heart Hospital, Anyang, South Korea

Gwang-Cheon Jang, MD, PhD , Pediatrics, NHIS Ilsan Hospital, Ilsan, South Korea

Hyeon-Jong Yang, MD, PhD , Pediatrics, Soonchunhyang University College of Medicine, Seoul, South Korea

Bok-Yang Pyun, MD, PhD. , Pediatrics, Soonchunhyang University College of Medicine, Seoul, South Korea

Ji-Won Kwon, MD , Seoul National University Bundang Hospital, Seongnam, South Korea

Myung Hyun Sohn, MD, PhD , Department of Pediatrics and Institute of Allergy, Yonsei University College of Medicine, Seoul, South Korea

Kyu-Earn Kim, MD, PhD , Department of Pediatrics and Institute of Allergy, Yonsei University College of Medicine, Seoul, South Korea

Jinho Yu, MD, PhD , Asan Medical Center Seoul Korea, Seoul, South Korea

Soo-Jong Hong, MD, PhD , Research Center for Standardization of Allergic Diseases, University of Ulsan College of Medicine, Seoul, South Korea

Jung Hyun Kwon, MD , Department of Pediatrics, Korea University College of Medicine, Seoul, Korea, Seoul, South Korea

Sung-Won Kim , Pusan Saint Maria Hospital, Pusan, South Korea

Tae-Won Song, MD , Ilsan Paik Hospital, Koyang, South Korea

Woo Kyung Kim , Seoul Paik Hospital, Seoul, South Korea

Hyung Young Kim, MD , Department of Pediatrics, Pusan National University Yangsan Hospital, Yangsan, South Korea

Youhoon Jeon, MD, PhD , Department of Pediatrics, Dongtan Sacred Heart Hospital, College of Medicine, Hallym University, Hwaseong, South Korea

Yong Ju Lee, MD , Hallym Sacred Heart Kangnam Hospital, Seoul, South Korea

Hae Ran Lee, MD, PhD , Pediatrics, Hallym University Medical Center, Anynag, South Korea

Hye-Young Kim , Department of Pediatrics, Medical Research Institute of Pusan National University Hospital, Busan, South Korea

Youngmin Ahn , Eulji University Hospital, Seoul, South Korea

Hye-Yung Yum, MD, PhD , Department of Pediatrics, Seoul Medical Center, Seoul, South Korea

Dongin Suh, MD , Department of Pediatrics, Seoul National University Hospital, Seoul, South Korea

Hyun Hee Kim, MD , The Catholic University of Korea, Seoul, South Korea

Jin Tack Kim, MD , The Catholic University of Korea, Seoul, South Korea

Jeong Hee Kim, MD, PhD , Department of Pediatrics, Inha University Hospital, Incheon, Seoul, South Korea

Kyung Won Kim, MD, PhD , Department of Pediatrics and Institute of Allergy, Yonsei University College of Medicine, Seoul, South Korea

Yong Mean Park, MD, PhD , Dept. of Pediatrics, Konkuk University School of Medicine, Seoul, South Korea

Sooyoung Lee, MD, PhD , Department of Pediatrics, Ajou University School of Medicine, Suwon, South Korea

Sooyoung Lee, MD, PhD , Department of Pediatrics, Ajou University School of Medicine, Suwon, South Korea

Background : The incidence of anaphylaxis has been increasing in western countries. Although anaphylaxis is recognized as an important life-threatening condition, no nationwide report has yet investigated the clinical features of anaphylaxis in Korean children.

Objective : We sought to investigate the clinical features of anaphylaxis in Korean children.

Methods : A retrospective medical record review was performed on children patients diagnosed with anaphylaxis between 2009 and 2013 in 23 tertiary hospitals of South Korea

Results : A total 991 cases (66% male, mean age 5.89±5,24) were reported, with 36.6% below 2 years of age. The most common past medical history was food allergy. A previous reaction to the same allergen was reported by 23.1%. Cutaneous symptoms (96.1%) were the most common symptoms followed by respiratory (85.0%), gastrointestinal (26.6%), neurologic (15.5%), and cardiovascular (14.3%). Although, cardiovascular symptoms of anaphylaxis were rare in young children (7.7%), cardiovascular symptoms were increased with age. Cardiovascular symptoms were common in  reactions caused by insect sting(50.0%). The mainstay of first-line treatment in hospital included antihistamine (61.2%), corticosteroids (42.2%) and epinephrine(34.0%). Epinephrine auto-injectors were prescribed for 26.6%.

Conclusion :  We identified differences in the symptoms of anaphylaxis according to age and triggers. Rate of use of epinephrine as the first-aid medication is too low, and prescription rate of adrenalin auto-injector is too low regardless of age of patients.