Saturday, 17 October 2015
Hall D1 Foyer (Floor 3) (Coex Convention Center)
Sung-Min Park, MD
,
Department of Dermatology, Pusan National University Yangsan Hospital, Yangsan, South Korea
Won-Ku Lee, MD
,
Department of Dermatology, Pusan National University, Pusan, South Korea
Jeong-Min Kim, MD
,
Department of Dermatology, Pusan National University Yangsan Hospital, Yangsan, South Korea
Gun-Wook Kim, MD
,
Department of Dermatology, Pusan National University, Pusan, South Korea
Je-Ho Mun, MD
,
Department of Dermatology, Pusan National University Yangsan Hospital, Yangsan, South Korea
Hoon-Soo Kim, MD
,
Department of Dermatology, Pusan National University, Pusan, South Korea
Margaret Song, MD
,
Department of Dermatology, Pusan National University, Pusan, South Korea
Hyun-Chang Ko, MD
,
Department of Dermatology, Pusan National University Yangsan Hospital, Yangsan, South Korea
Moon-Bum Kim, MD, PhD
,
Department of Dermatology, Pusan National University, Pusan, South Korea
Byung Soo Kim, MD, PhD
,
Department of Dermatology, Pusan National University, Pusan, South Korea
A) Background: Hand eczema is a common inflammatory dermatosis which influences the quality of life especially when it comes to accompanying itching. However, there is no research regarding the characteristics of itch and neurologic association in hand eczema so far. We performed this study to objectify the influence on quality of life in patients with hand eczema and to investigate the association with cutaneous nerve.
B) Methods: we conduct a hand eczema severity scoring using HECSI score, a questionnaire contains Leuvin itch scale and dermatology life quality index(DLQI), and a neurologic exam using von-Frey filament and neurometer.
C) Results: Forty-four patients were enrolled the study and 36 patients were also done neurologic examination. Itch occurred at least once daily in all study patients, and finger and palm were the most commonly affected itch areas (25.0%). The Leuvin itch scale was directly proportional to HECSI score (p=0.272), and DLQI was inversely proportional to it (p=0.019). The sensory threshold force measured by von-Frey filament was significantly higher in lesion than normal skin (p<0.05) and the pain threshold using neurometer was also significantly decreased in lesion (p<0.05).
D) Conclusion: This study is a unique trial which describes the characteristics of itch experienced in hand eczema and investigates the relationship between hand eczema and cutaneous nerve. We thought it could be a good basis in development of future therapeutic modalities such as neurotransmitters in hand eczema.
