Marilyn Urrutia Pereira, MD, PhD,
,
Pediatric Program of Asthma Prevention (PIPA), Brazilian Sociaty, Uruguaina, Brazil
Dirceu Sole, MD, PhD
,
Sao Paulo Federal University, Brazilian Society, Sao Paulo, Brazil
Nelson Rosario Filho, MD PhD
,
Pediatrics, University of Parana, Curitiba, Brazil
Juan C. Sisul, MD,
,
State Director Gard/ARIA, Paraguay
Alfonso Mario Cepeda, MD,
,
Pediatria, Hospital Universitario Metropolitano, Barranquilla, Colombia
Marylin Valentin Rostan, MD,
,
Montevideo, Rafael Barradas 1671, Montevideo, Uruguay
Herberto Jose Chong Neto, MD, PhD
,
Pediatric, Universidade Federal Do Paraná, Curitiba, Brazil
Raúl Lázaro Castro Almarales, MD, MSc
,
Allergens Department, National Center of Bioproducts, Mayabeque, Cuba
Miguel Alejandro Medina Avalos, MD,
,
Pediatric, Servicio De Alergologia Del Hospital Issste, Veracruz,, Mexico
Hector Badellino, MD, PhD
,
Pediatric, Clínica Regional Del Este, San Francisco-Cordoba, Argentina
Antonio Castillo, MD,
,
Pediatric, Centro De Medicina Avanzada Dr. Abel González, Santo Domingo, Dominican Republic
Claudia Almendarez, MD,
,
Pediatric, Centro De Asma y Alergia, Tagucigalpa, Honduras
Caridad Sanchez Silot, MD, MSc
,
Allergology Service, Pediatric, University Hospital Infantil Sur, Santiago de Cuba, Cuba
Jennifer Avila, Enfermeira
,
Pediatria, Pediatric Program of Asthma Prevention (PIPA), Uruguaiana, Brazil
Jose Santos Lozano Saenz, MD,
,
Pediatric, Centro medica San Angel, Xalapa, Mexico
Veronica Acosta, MD,
,
Pediatric, Hospital Dr Avelino L Castelán, Resistencia-Chaco, Argentina
Felicia Berroa Rodriguez, MD,
,
Pediatric, Centro De Medicina Avanzada Dr. Abel González, Santo Domingo, Dominican Republic
Mirta Alvarez Castello, MD
,
Allergology Service, University Hospital Calixto García, Havana, Cuba
Carmen Fernandez, MD,
,
Pediatric, Centro Pediátrico Paidos – Universidad Nacional Del Este, Asunción, Paraguay
Mayda González León, MD
,
Docent Polyclinic "Pedro Fonseca", Cuban Society of Integral General Medicine Member, Cuban Society of Allergy , Asthma and Clinical Immunology, Member, Cuban Society of Immunology Member,, Havana, Cuba
Maria Carolina Manotas, MD,
,
Pediatric, Hosp Universitario Metropolitano, Barranquilla, Colombia
Michel De La Cruz Betances, MD,
,
Pediatric, Centro De Medicina Avanzada Dr. Abel González, Santo Domingo, Dominican Republic
Background: Atopic dermatitis (AD) has been associated with impairment of sleep. The aim of this study was
to evaluate sleep disorders in AD Latin-American children (4 to 10 years) from 10 countries, and in normal controls (C)
Methods:parents from 454 C and 340 AD children followed in reference clinics answered the Children Sleep Habits Questionnaire (CSHQ) that is an one-week retrospective questionnaire composed by 33 questions and divided in 7 subscales (bedtime resistance, sleep duration, sleep anxiety, night awaking, parasomnias, sleep-disordered breathing and daytime sleepness). Total CSHQ scale and subscales were compared between C and DA groups. Spearman’s correlation coefficient between SCORAD (Scoring atopic dermatitis) with all subscales and total CSHQ were also obtained.
Results: C and DA groups were similar regarding age, however, significantly higher values for total CSHQ (62.2±16.1 vs53.3±12.7, respectively) and subscales were observed among DA children in comparison to C, and they were higher among those with moderate (54.8%) or severe (4.3%) AD. Except for sleep duration (r=-0.02, p=0.698), there were a significant Spearman’s correlation index for bedtime resistance (0.24, p<0.0001), sleep anxiety (0.29, p<0.0001), night awaking (0.36, p<0.0001), parasomnias (0.54, p<0.0001), sleep-disordered breathing (0.42, p<0.0001), daytime sleepiness (0.26, p<0.0001) and total CSHQ (0.46, p<0.0001).
Conclusions: although properly treated, Latin-American children with AD showed to have sleep disorders evaluated by the CSHQ. Children with moderate to severe forms of AD were those who had the biggest changes in CSHQ.
