7-3OAS Atopic dermatitis and sleep disorders in latin American children

Friday, 16 October 2015: 11:30 - 11:45
Room R2 ABC (Floor 3) (Coex Convention Center)

Marilyn Urrutia Pereira, MD, PhD, , Pediatric Program of Asthma Prevention (PIPA), Brazilian Sociaty, Uruguaina, Brazil

Dirceu Sole, MD, PhD , Sao Paulo Federal University, Brazilian Society, Sao Paulo, Brazil

Nelson Rosario Filho, MD PhD , Pediatrics, University of Parana, Curitiba, Brazil

Juan C. Sisul, MD, , State Director Gard/ARIA, Paraguay

Alfonso Mario Cepeda, MD, , Pediatria, Hospital Universitario Metropolitano, Barranquilla, Colombia

Marylin Valentin Rostan, MD, , Montevideo, Rafael Barradas 1671, Montevideo, Uruguay

Herberto Jose Chong Neto, MD, PhD , Pediatric, Universidade Federal Do Paraná, Curitiba, Brazil

Raúl Lázaro Castro Almarales, MD, MSc , Allergens Department, National Center of Bioproducts, Mayabeque, Cuba

Miguel Alejandro Medina Avalos, MD, , Pediatric, Servicio De Alergologia Del Hospital Issste, Veracruz,, Mexico

Hector Badellino, MD, PhD , Pediatric, Clínica Regional Del Este, San Francisco-Cordoba, Argentina

Antonio Castillo, MD, , Pediatric, Centro De Medicina Avanzada Dr. Abel González, Santo Domingo, Dominican Republic

Claudia Almendarez, MD, , Pediatric, Centro De Asma y Alergia, Tagucigalpa, Honduras

Caridad Sanchez Silot, MD, MSc , Allergology Service, Pediatric, University Hospital Infantil Sur, Santiago de Cuba, Cuba

Jennifer Avila, Enfermeira , Pediatria, Pediatric Program of Asthma Prevention (PIPA), Uruguaiana, Brazil

Jose Santos Lozano Saenz, MD, , Pediatric, Centro medica San Angel, Xalapa, Mexico

Veronica Acosta, MD, , Pediatric, Hospital Dr Avelino L Castelán, Resistencia-Chaco, Argentina

Felicia Berroa Rodriguez, MD, , Pediatric, Centro De Medicina Avanzada Dr. Abel González, Santo Domingo, Dominican Republic

Mirta Alvarez Castello, MD , Allergology Service, University Hospital Calixto García, Havana, Cuba

Carmen Fernandez, MD, , Pediatric, Centro Pediátrico Paidos – Universidad Nacional Del Este, Asunción, Paraguay

Mayda González León, MD , Docent Polyclinic "Pedro Fonseca", Cuban Society of Integral General Medicine Member, Cuban Society of Allergy , Asthma and Clinical Immunology, Member, Cuban Society of Immunology Member,, Havana, Cuba

Maria Carolina Manotas, MD, , Pediatric, Hosp Universitario Metropolitano, Barranquilla, Colombia

Michel De La Cruz Betances, MD, , Pediatric, Centro De Medicina Avanzada Dr. Abel González, Santo Domingo, Dominican Republic

Background: Atopic dermatitis (AD) has been associated with impairment of sleep. The aim of this study was to evaluate sleep disorders in AD Latin-American children (4 to 10 years) from 10 countries, and in normal controls (C)

Methods:parents from 454 C and 340 AD children followed in reference clinics answered the Children Sleep Habits Questionnaire (CSHQ) that is an one-week retrospective questionnaire composed by 33 questions and divided in 7 subscales (bedtime resistance, sleep duration, sleep anxiety, night awaking, parasomnias, sleep-disordered breathing and daytime sleepness). Total CSHQ scale and subscales were compared between C and DA groups. Spearman’s correlation coefficient between SCORAD (Scoring atopic dermatitis) with all subscales and total CSHQ were also obtained.

Results: C and DA groups were similar regarding age, however, significantly higher values for total CSHQ (62.2±16.1 vs53.3±12.7, respectively) and subscales were observed among DA children in comparison to C, and they were higher among those with moderate (54.8%) or severe (4.3%) AD. Except for sleep duration (r=-0.02, p=0.698), there were a significant Spearman’s correlation index for bedtime resistance (0.24, p<0.0001), sleep anxiety (0.29, p<0.0001), night awaking (0.36, p<0.0001), parasomnias (0.54, p<0.0001), sleep-disordered breathing (0.42, p<0.0001), daytime sleepiness (0.26, p<0.0001) and total CSHQ (0.46, p<0.0001).

Conclusions: although properly treated, Latin-American children with AD showed to have sleep disorders evaluated by the CSHQ. Children with moderate to severe forms of AD were those who had the biggest changes in CSHQ.