4052 Epidemiology of Anaphylaxis In Adults Treated In the Emergency Department, of the University Hospital of Monterrey N.L Mexico, During : 2005-2010

Wednesday, 7 December 2011
Poster Hall (Cancún Center)

Maricruz Calva, MD , Regional Centre of Allergy and Clinical Immunology, University Hospital, Monterrey, Mexico

Sandra González-Díaz, MD, PhD , Regional Centre of Allergy and Clinical Immunology, University Hospital, Monterrey, Mexico

Alfredo Arias-Cruz, MD , Allergy and Clinical Immunology, University Hospital UANL, Monterrey, Mexico

Alejandra Macías-Weinmann , Regional Centre of Allergy and Clinical Immunology, University Hospital, Monterrey, Mexico

Lucía Leal, MD, PhD , Regional Centre of Allergy and Clinical Immunology, University Hospital, Monterrey, Mexico, Monterrey, Mexico

Arya González, MD , Regional Center of Allergy and Clinical Immunology, University Hospital, Monterrey, Mexico

Claudia Gallego, MD , Regional Center of Allergy and Clinical Immunology, University Hospital, Monterrey, Mexico

Diego Garcia-Calderin, MD , Regional Centre of Allergy and Clinical Immunology, University Hospital, Monterrey, Mexico

Karla Mejia, MD , Regional Centre of Allergy and Clinical Immunology, University Hospital, Monterrey, Mexico

Luis Dominguez, MD , Regional Centre of Allergy and Clinical Immunology, University Hospital, Monterrey, Mexico

Background: The risk of anaphylaxis ranges from 0.2% to 0.7%. The objective of this study was to describe the causes, clinical features and complications of patients with anaphylaxis treated in the emergency department of our hospital.

 Materials and Methods : A prospective, observational and descriptive survey was conducted  for assessing adult patients with  diagnosis of anaphylaxis from March 2005-2010. Information was obtained from the medical records and from    a questionnaire was that completed for the patients and a relative. The information included, triggers, demographics, allergy history and clinical characteristics of the current episode.   All the cases were followed  to their outcome.

Results: We documented 45 cases of anaphylaxis. 26 patients (58%) were male.The most common causes of anaphylaxis were: drug (49%) food (20%) and poison hymenoptera venom (16%). The most common clinical signs ando symptoms included: dyspnea (69%), nausea (58%) and hypotension (56%). 44% of patients came to emergency departments in the course of 30 minutes after onset of symptoms while the 29% took 30 minutes to 1 hour and 27% more than 1 hour. Among the associated diseases, hypertension 13% and rhinitis (11%). In 85% of the cases, patients remained under observation for 3-12 hours were the most frecuent discharged. 7 patients were hospitalized, and 4   step to intensive care and were discharged without complications.

Conclusions: Anaphylaxis is not uncommon in our environment. drugs are the most common cause as reported in the literature. The most frequent clinical manifestations are respiratory and gastrointestinal followed.