1068 Immunological and Biochemical Parameters of CCl4 Treated Male Rates under the Effect of Samsum Ant Venom

Sunday, 7 December 2014
Exhibition Hall-Poster Area (Sul America)

Mohammed Alkhalifa, PhD , Zoology, King Saud University, Riyadh, Saudi Arabia

Anti-inflammatory effect of Samsum Ant Venom (SAV) in CCl4- treated males induced acute toxicity . CCl4 significantly increased the oxidative stress indicators in CCl4-injected rats. A notable rise  
of malondialdehyde (MDA) with a significant suppression of glutathione were observed  in the tissues of both  liver and spleen.  A significant rise in the total leucocyte counts with notably  high neutrophil percentage was detected  in CCl4-injected rats. Also CCl4 caused  significant rise in  the triglycerides, cholesterol, creatinine, urea and ALT, and lower the level of total protein. The dose, 100 μg/kg of SAV was used to significantly establish  all the parameters.  Beneficiary aspect of correlation between SAV and the animal model health was noticed in normal structure of  tissues of both spleen and liver with  normal distribution of  leucocytes, the immune cells in the CC4 injected rates.