Methods: in this case report, we describe drug eruption associated with Omeprazole in a patient previously diagnosed with Still Syndrome.
Results: after extensive medical history taken by the allergist, the patient revealed chronic use of Omeprazole for over ten years, so far not reported for the same. Thus, the suspension was indicated in the use of drug rash with complete remission. Endocrine, skin, nerve and muscle disorders, although rare, may also occur in the patient who makes use of such drug. In this sense, the cutaneous reactions of the type erythematosus rash are symptoms that, although rare, may also manifest in patients, as reported in this case. Diseases like Still syndrome can mimic dermatological picture with the same cutaneous manifestations (OWLIA MB, MEHRPOOR G), which contributed to the difficult elucidation of this urticaria and angioedema diagnosis.
Conclusions: the resolution of the urticária and angioedema presented by the patient was only possible thanks to an accurate anamnesis with her, added to the fact of medical knowledge about the medicinal drug (reaction to Omeprazol), including those more rare, which ratifies the need for critical thinking reactions and pharmacological knowledge of the professional in your work routine.