Reporting a case of anti-polysaccharide antibody deficiency, facilitating the early diagnosis.
Methods:
analysis of medical records was conducted to obtain detailed medical history.
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Results:
Reporting a case of anti-polysaccharide antibody deficiency, facilitating the early diagnosis.Results: GSF, 3 years old, male, born cesarean section, term delivery. On 8 months from the birth, it was made the diagnosis of bronchopneumonia, evolving with recurrent fever. When he was 1 year old it was diagnosed with fever with no cause and in the CBC appeared leukocytosis,high level of C-reactive protein and erythrocyte sedimentation rate and too, normal immunoglobulins. When he was 2 years old he was diagnosed with tonsillitis five times that evidenced difficulty in treatment, most often requiring 2 kindes of antibiotics. In this period the patient received the 23-valent pneumococcal vaccine .When he was 3 years old he had repeated tonsillitis,It was opted by the introduction of prophylactic amoxicillin, that result clinical improvement.Tests were ordered: X-rays and computed tomography of the chest that had normal results. Immunophenotyping unchanged, serology for measles and rubella IgM nonreactive, isohemagglutinins: anti A: 128/64 anti B / ABO / RhO +, complement fractions unchanged HIV nonreactive. Pneumococcal serology: serotype 4 <0.5 / serotype 6B <0.5 / serotype 9V <0.5 / Serotype 14 <0.5 / serotype 18C = 0.9 / = 1.2 Serotype 19F / A serotype 23 F <0, 5.All serotypes are less than 1.3 mg / ml. Currently, this patient, treated with prophylactic antibiotics, will receive the 13-valent pneumococcal vaccine. If the patient will not respond to treatment with vaccine and to evolve with persistent infections, It will be examined on the possibility of infusion of human gammglobulin.
Conclusions:
According to this case reported above, the early diagnosis is of utmost importance. The diagnosis is not always completed because the lack of medical information regarding primary immunodeficiencies.