2055 Asthma control and quality of life of pregnant women

Monday, 8 December 2014
Exhibition Hall-Poster Area (Sul America)

José Ângelo Rizzo, PhD , Research Center for Allergy and Clinical Immunology, Hospital Das Clínicas - Universidade Federal De Pernambuco., Recife, Brazil

Décio Medeiros, PhD , Research Center for Allergy and Clinical Immunology, Federal University of Pernambuco, Recife, Brazil

Emanuel Sarinho, PhD , Federal University of Pernambuco, Brazil

Aline Duarte Maranhão, MD , Obstetrics, Hospital Das Clínicas - Universidade Federal De Pernambuco., Recife, Brazil

Almerinda Rego Silva, MD , Allergy and Clinical Immunologr, Hospital Das Clínicas - Universidade Federal De Pernambuco., Recife, Brazil

Mauro Aguiar, MD , Department of Gynecology and Obstetrics, Federal University of Pernambuco, Recife, Brazil

Elias Melo Jr, PhD , Obstetrics, Hospital Das Clínicas - Universidade Federal De Pernambuco., Recife, Brazil

Background: Asthma is the most prevalent chronic disease in pregnant patients with risks for the patient and the fetus. Proper treatment is able to control the disease. It is important to assess if the control of symptoms is associated with improved quality of life for patients. The objetive was evaluate the association between asthma control and quality of life in asthmatic pregnant women. 

Methods: A descriptive observational study with 51 pregnant patients with bronchial asthma under treatment at the Clinic of Asthma in Pregnancy of the Hospital das Clínicas - Federal University of Pernambuco (Recife - Brazil). Asthma control was determined by the asthma control test (ACT) and the classification of the Global Initiative for Asthma (GINA), the quality of life was assessed by the St. George's Respiratory Questionnaire (SGRQ). 

Results: The mean gestational age of the patients was 24.4 ± 6.8 weeks. There was agreement between the assessment of asthma control by the ACT and GINA (kappa = 0,828). Significant negative correlations between the scores of the ACT and all SGRQ scores were observed: the total (r = -0.73); symptoms (r = -0.739); activities (r = -0.605) and psychosocial impact (r = -0.604). Patients with intermittent asthma and elevated forced expiratory volume in 1s (FEV1) showed higher score of quality of life.

Conclusions: The status of asthma control is associated with better health-related quality of life in asthmatic pregnant women, but further studies are needed with this particular group of patients to quantify and determine the real influence of disease control on quality of life during pregnancy.