ten years. As the use of LTRAs increases, our knowledge with respect to their side effects increases as well.
Objective: Our study was aimed to evaluate the observed side effects of LTRAs used in patients with astma.
Methods: 1024 patients who were only treated with LTRAs owing to astma or early wheezing were included in the
study for a five-year period. The observed side effects of LTRAs in these patients were retrospectively investigated.
The side effects were divided into two parts as psychiatric and non- psychiatric.
Results: It was found out that 67.5% of 41 (4%) patients in whom side effects were observed was male and their
average age was 6.5. The rate of patients with asthma was 63.41% and it was 36.58% for patients with early
wheezing. It was determined that sex, age and diagnosis (early wheezing or asthma) of the patients were
ineffective in the emergence of side effects. The average period for the emergence of side effects was the fisrt
month. It was observed that hyperactivity was the most frequently seen psychiatric side effect and abdominal pain
was the non-psychiatric side effect.
Conclusions: The side effects of LTRAs were common in children. Therefore, patients must be informed at the
beginning of the treatment and they must be evaluated at certain intervals.