Tuesday, 9 December 2014: 09:35 - 10:00
Grand Ballroom (Sul America)
John Cambier
,
Department of Immunology, University of Colorado Denver and National Jewish Health, Denver, CO
Learning Objectives:
Tracking Destiny of Anergic B cells Compromised by Autoimmunity Risk Alleles.John C. Cambier, Department of Immunology and Microbiology, University of Colorado School of Medicine, Denver, Colorado, USA
Tracking Destiny of Anergic B cells Compromised by Autoimmunity Risk Alleles.John C. Cambier, Department of Immunology and Microbiology, University of Colorado School of Medicine, Denver, Colorado, USA
Learning Objectives:
1) Understand mechanisms of silencing of autoreactive B cells.
2) Understanding molecular signaling circuitry involved in B cell antigen receptor signaling.
3) Appreciate the role of autoimmunity risk alleles and normal counterparts in regulation of B cell antigen receptor signaling, cell activation, and differentiation.