2070 S.L.I.T. RUSH Immunotherapy -Faster REACH to Maintenance Pleatu-India

Saturday, 8 December 2012
Hall 4 (HICC)

Naren Pandey , Allergy & Asthma, Mediland Diagnostic Institute, India

Kaushik Chakraborty , Population Health, Barrackpore Population Health Research Foundation, India

Ramendra Nath Mitra

Ashim Kumar Sarkar

Anirban Neogi

Background:

Slit(sub lingual immunotherapy Rush immunotherapy was tried on some patients to evolve some faster and affordable immunotherapy modality to make the patient achieve the maintenance pleatu within a very short time. Conventional method of immunotherapy is administered with long durations; rush immunotherapy is super fast methodology in attaining the maintenance/boosting module, which requires hospitalization and other precautionary methods, and multiple allergen vaccines to be administered within short span of time. But in this method, it was found that within 15-20 days the relief of the immunotherapy was reached. 

Methods:

186 patients out of which 48 with urticaria allergy and 138 with allergic Rhinitis &Bronchial Asthma were selected. The therapy consists of administration of four vials of allergen extracts, 1st vial: 1:25,00, 2nd vial 1:2,50, 3rd vial 1:25, and 4th vial 1:10 dil. The 1st & the 2nd concs were administered in daily 6 hourly schedules in a graphically rising manner. The patients had been given pre-medication. Blood examination and IgG & IgE level estimation were done before & after 8 weeks.

1) M.P.BIRLA MEDICAL EDUCATION & RESEARCH CENTRE

  ,2)MEDILAND DIAGNOSTIC INSTITUTE,KOLKATA

  3) HOPE SUPERSPECIALITY HOSPITAL,PURNEA,BIHAR

Results:

some of the patients showed local skin reactions which subsided without drugs and no systemic reaction was noted. There was substantial decrease in IgE & increased IgG level, significant & marked satisfactory relief was observed in the patients symptomatology, 

Conclusions:  procedure was graded as a very fast & affordable & SAFE immunotherapy.