Methods: A prospective, randomized, parallel-group, open-label study of desloratadine effectiveness in children with persistent allergic rhinitis in age from 2 to 16 years in 4 weeks. The effectiveness of therapy is monitored by clinical symptoms and rhinomanometry.
Results: The study showed that desloratadine is an effective treatment for persistent allergic rhinitis in children of different age groups, well-controlled nasal and other symptoms of allergic rhinitis, nasal congestion helps to reduce and restore nasal breathing. The best effect is seen with regard to histamine-induced symptoms (itching, sneezing, rhinorrhea). In children with allergic rhinitis and asthma therapy desloratadine additionally contributes to the positive dynamics of symptoms of asthma.
Conclusions: The effectiveness of desloratadine therapy in children with isolated allergic rhinitis is higher than in patients with concomitant asthma.