We investigated the association with prevalence of metals including nickel, chromium, cobalt, and mercury by patch test and orthodontic appliance. Additionally we investigated the coincidence of resin and colophonium sensitization which is adhesive materials of orthodontic appliance with the patients with orthodontic appliance. In total, 150 patients were included and performed patch test. The patients characteristics including orthodontic appliance history were collected with a questionnaire and clinical investigation.
The incidence of metal allergy was significantly high in the patients with experience of orthodontic appliance. Especially nickel and cobalt allergy were more significantly correlated with orthodontics history. In metal allergy, orthodontics could be an important role.