Methods: 64 subjects with high level of TIgE were tested for serum sIgE-derp1 and sIgE-Af by using ImmunoCAP 100.
Result： 68.8% (44/64) patients were sensitive to HDM while 40.6% (29/64) were sensitive to aspergillosis. What’s more, 37.5% (24/64) patients could be detected sIgE (derp1,Af) while 15/64(23.4%) patients were found sIgE(derp1,Af)-free. 20/64 (31.3%) patients were merely sensitive to HDM while 5/64 (7.8%) were sensitive to Aspergillosis. Among the patients with TIgE higher than 1000ku/L, those patients sensitive to HDM was significantly more than those sensitive to Aspergillosis (ka=9.00,t= P<0.01). sIgE-Af (r=0.410) was correlated more with TIgE than sIgE-derp1 (r=0.228) was (P<0.05).
Conclusion：Most of the patients with high level of TIgE, complicated with respiratory diseases, were more likely sensitive to HDM rather than Aspergillosis. Compared to sIgE against HDM, sIgE-Af contributed more to the level of TIgE. The detection of sIgE against HDM and Aspergillosis was important for the patients complicated with respiratory and high level of TIgE.