Friday, 16 October 2015
Hall D1 Foyer (Floor 3) (Coex Convention Center)
Objective: Diagnosis of asthma is challenging in preschool children who wheeze. The Asthma Predictive Index (API) is used as a tool to predict asthma and decide whether to initiate controller therapy in preschool children. The aims of this study were to investigate whether the API was associated with doctor’s diagnosis of asthma in preschool children with recurrent wheeze and find the most relevant criteria to asthma. Methods: We performed a population-based, cross-sectional study with 933 children aged 4-6 years. A total of 900 children completed a modified International Study of Asthma and Allergies in Childhood questionnaire and 121 children with recurrent wheeze were enrolled. Recurrent wheeze was defined as having a lifetime wheeze more than 3 times. Results: The prevalence of doctor’s diagnosis of asthma was 39%. The percentage of children who met the API was 79.5% (major; 64.4%, minor; 57.5%). Positive API showed tendency of association with doctor’s diagnosis of asthma in preschool children with recurrent wheeze (OR; 4.69, 95%CI; 0.97-22.61). Among the API criteria, only doctor’s diagnosis of allergic rhinitis (AR) was significantly associated with asthma (OR; 4.16, 95%CI; 1.86-9.30). Conclusions: Doctor’s diagnosis of AR is likely to have the highest association with asthma among the criteria of API in preschool children with recurrent wheeze.