Presentation: <span>the Association of Asthma Predictive Index with Asthma in Preschool Children with Recurrent Wheeze</Span> ( World Allergy Congress)

Friday, 16 October 2015

Hall D1 Foyer (Floor 3) (Coex Convention Center)

Sung Joo Park, MD , Pediatrics, Kangbuk Samsung Hospital/Sungkyunkwan University School of Medicine, Seoul, South Korea

Ji-Won Kwon, MD , Seoul National University Bundang Hospital, Seongnam, South Korea

Woo Kyung Kim , Seoul Paik Hospital, Seoul, South Korea

Hyung Young Kim, MD , Department of Pediatrics, Pusan National University Yangsan Hospital, Yangsan, South Korea

Hyo-Bin Kim, MD , Department of Pediatrics, Inje University Sanggye Paik Hospital, Seoul, South Korea

Ju-Hee Seo, MD , Department of Pediatrics, Korea Cancer Center Hospital, Seoul, South Korea

So-Yeon Lee, MD , Department of Pediatrics, Hallym University Sacred Heart Hospital, Anyang, South Korea

Gwang-Cheon Jang, MD , Pediatrics, National Health Corporation Ilsan Hospital, Seoul, South Korea

Young-Ho Jung, MD , Department of Pediatrics, Bundang CHA Medical Center, CHA University School of Medicine, Seongnam, South Korea

Soo-Jong Hong, MD, PhD , Department of Pediatrics, Childhood Asthma Atopy Center, Enviromental Health Center, University of Ulsan College of Medicine,, Asan Medical Center, Seoul, South Korea

Byoung-Ju Kim, MD , Department of Environmental Health, University of Cincinnati College of Medicine, Cincinnati, OH

Dae-Jin Song, MD , Pediatrics, Guro Hospital, Seoul, South Korea

Yun Seok Yang, MD , Pediatrics, Kangbuk Samsung Hospital, Seoul, South Korea

Jung Yeon Shim, MD , Pediatrics, Kangbuk Samsung Hospital/Sungkyunkwan University School of Medicine, Seoul, South Korea

Objective: Diagnosis of asthma is challenging in preschool children who wheeze. The Asthma Predictive Index (API) is used as a tool to predict asthma and decide whether to initiate controller therapy in preschool children. The aims of this study were to investigate whether the API was associated with doctor’s diagnosis of asthma in preschool children with recurrent wheeze and find the most relevant criteria to asthma. Methods: We performed a population-based, cross-sectional study with 933 children aged 4-6 years. A total of 900 children completed a modified International Study of Asthma and Allergies in Childhood questionnaire and 121 children with recurrent wheeze were enrolled. Recurrent wheeze was defined as having a lifetime wheeze more than 3 times. Results: The prevalence of doctor’s diagnosis of asthma was 39%. The percentage of children who met the API was 79.5% (major; 64.4%, minor; 57.5%). Positive API showed tendency of association with doctor’s diagnosis of asthma in preschool children with recurrent wheeze (OR; 4.69, 95%CI; 0.97-22.61). Among the API criteria, only doctor’s diagnosis of allergic rhinitis (AR) was significantly associated with asthma (OR; 4.16, 95%CI; 1.86-9.30). Conclusions: Doctor’s diagnosis of AR is likely to have the highest association with asthma among the criteria of API in preschool children with recurrent wheeze.

3195 the Association of Asthma Predictive Index with Asthma in Preschool Children with Recurrent Wheeze