4095 Vitamin D Deficiency As a Risk Factor of Atopic Dermatitis in Korean Female Adolescents

Saturday, 17 October 2015
Hall D1 Foyer (Floor 3) (Coex Convention Center)

Kyung Suk Lee, MD, PhD , Department of Pediatrics, Bundang CHA Medical Center, CHA University School of Medicine, Seongnam, South Korea

Sun Hee Choi, MD, PhD , Department of Pediatrics, Kyung Hee University Hospital at Gangdong, Seoul, South Korea

Hye Rim Park, MD , Department of Pediatrics, Kyung Hee University Hospital, Seoul, South Korea

Jun Hyuk Song, MD , Department of Pediatrics, Myongji Hospital, Goyang-si, Gyeonggi-do, South Korea

Myung Sung Kim, MD , Idream Children Hospital, Daegu, South Korea

Won Seok Lee, MD , Total Control Center, Gangwon Fire Headquarters, Chuncheon-si, Gangwon-do, South Korea

Yeong Ho Rha, MD, PhD , Department of Pediatrics, Kyung Hee University Hospital, Seoul, South Korea

BACKGROUD: Vitamin D deficiency be widely known that is associated with the prevalence of atopic dermatitis (AD). However, little is known the association between atopic dermatitis and vitamin D level in Korean adolescents. We evaluated whether the occurrence of atopic dermatitis is related to serum vitamin D levels in the general Korean adolescents.

METHODS: We obtained data of 2,748 adolescents (from 12 to 18 years old) from the fourth and fifth Korean National Health and Nutrition Examination Survey (2008 to 2012). We divided 3 groups according to level of Vitamin D (<15 ng/ml, 15< - <25 ng/ml, >25 ng/ml). Multivariate regression analysis was performed to find which Vitamin D deficiency could be risk factors for AD.

RESULTS: Adolescents with diagnosed AD were 10.2% in all participants answered to questionnaires. VitaminD level of total, male and female adolescents was 16.2 ng/ml, 16.65 ng/ml and 15.65 ng/ml, respectively. After adjusting for obesity, age, income quartile, exercise, parental allergic history, drinking, and smoking, lower serum vitamin D level didn’t associated with AD of total and male adolescents, but significantly related to AD in female adolescents (adjusted odd ratio (aOR)=5.91, p=0.02 in group of <15 ng/ml; aOR=8.37, p=0.01 in group of 15< - <25 ng/ml).

CONCLUSIONS: This study suggested vitamin D deficiency is a risk factor of AD in Korean female adolescents. Further studies are required to find the reason why vitamin D level in females is lower than in males and a policy needs to prevent vitamin D deficiency