Thursday, 15 October 2015
Hall D1 Foyer (Floor 3) (Coex Convention Center)
Jin Hyeok Jeong, MD, PhD
,
Department of Otorhinolaryngology-Head and Neck Surgery, Hanyang University College of Medicine, Seoul, South Korea
Tae Wook Kang, MD
,
Department of Otorhinolaryngology-Head and Neck Surgery, Hanyang University College of Medicine, Seoul, South Korea
Han Seok Yoo, MD
,
Department of Otorhinolaryngology-Head and Neck Surgery, Hanyang University College of Medicine, Seoul, South Korea
Yong Hee Cho, MD
,
Department of Otorhinolaryngology-Head and Neck Surgery, Hanyang University College of Medicine, Seoul, South Korea
Seok Hyun Cho, MD, PhD
,
Department of Otorhinolaryngology-Head and Neck Surgery, Hanyang University College of Medicine, Seoul, South Korea
Kyung Rae Kim, MD, PhD
,
Department of Otorhinolaryngology-Head and Neck Surgery, Hanyang University College of Medicine, Seoul, South Korea
Background : In asthma patients, chronic rhinosinusitis with nasal polyp tend to have high recurrence rate after surgery, and gets better and worse along the clinical course of asthma. The oral steroid treatment is often used in these cases because of poor effect of local nasal steroid treatment. Side effect of long-term oral steroid is considered to be a serious concern for the physicians. The off-label use of budesonide nasal irrigation was introduced recently for post operative management of patients with chronic rhinosinusitis. The safety and effect of budesonide nasal irrigation is being accepted to many physicians. The objective of this study is to evaluate the efficacy of postoperative steroid irrigation in asthma patients.
Methods : Prospective study was done on 12 chronic rhinosinusitis patients with nasal polyp and asthma who used oral steroid treatment due to recurred or worsen disease. The 22-item Sinonasal Outcomes Test (SNOT-22) and Lund-Kennedy endoscopy scores were performed before nasal budesonide irrigation, 1, 2, 4, and 6 months after the irrigation.
Results : The subjects were of 3 male and 9 female patients and the mean age of the patients were 49.9±7.3. SNOT-22 score was 30.8±14.4 before irrigation followed by 17.8±16.6 after 1 month, 14.8±11.1 after 2 months, 14.9±10.9 after 4 months and 14.17±8.7 after 6 months of irrigation. SONT-22 scores were significantly improved with irrigation (p=0.03) Endoscopy score was 7.4±4.7 before the irrigation followed by 3.5±3.3 after 1 month, 1.5±1.8 after 2 months, 1.7±1.5 after 4 months and 2.2±2.7 after 6 months. The scores were significantly improved with irrigation (p<0.001).
Conclusions : Nasal irrigation with budesonide is considered to be an effective post operative treatment for chronic rhinosinusitis patients with asthma which recur frequently, reducing the use of oral steroid intake.
