Over a 28-days period 51 children patient underwent the long term stay with the medical treatment in medical institute in Metylovice. In total 31 girls and 20 boys in the same age with bronchial asthma fulfilled the inclusion criterion (GINA 2014) and were included in the study. In all patients, atopic status was evaluated by skin prick testing using common allergen extracts (grass and tree pollen, house dust mite, moulds, cat/dog extracts). Patients blood eosinophils leukocyte count, levels of total sesrum imunoglobulin E, serum eosinophil cationic protein and exhaled nitric oxide levels were determined.Daily the patients received 1500 IU of Vitamin D3 orally.
The object was to evaluate the effectiveness and benefits of long term stay for asthmatic children after the continuous treatment with vitamin D and physical exercises.The evaluation was done by the comparison of laboratory examination of blood and physical parameters in the beginning of the stay and in the end of the stay. It was determined the hypothesis that the long term stay has significant positive effect on level of vitamin D3 31.80 mmol/l in the beginning of the stay vs 45.58 mmol/l(p<0.001) and some parameters of physical fitness of children in the study done by modified Cooper’stest such as the test of abdominal muscles 18.45 pull s/min vs 27.15 pulls/min (p<0.001).
The climate stay with the exclusion of the negative influence of the environment with the activity of vitamin D3 led to a stabilisation of asthma without the need of treatment by salbutamol spray. Subsequently, the higher the intensity of rehabilitation exercises increased muscle strength and improved the quality of breathing.