Background: The role Helicobacter pylori (H. pylori) infection in the aetiology of atopy remains unclear, although a possible protective role has been hypothesized.
Objective: The aim of this study was to evaluate the prevalance of H. pylori in the atopic individuals.
Methods: We conducted a retrospective, observational and cross-sectional study which included 104 patients, aged between 18 and 70 years. Total serum IgE (Immage 800, Beckman Coulter, Ireland) and H.pylori IgG (DIA.PRO, Italy) were measured in all participants by using nephelometric method and ELISA respectively.
Results: One hundred four patients included in the study. The avarage age was 38, and 74 of the patients were female (71.2%). The average IgE was measured to be 165 IU / mL. Fifty-two (50%) patients were diagnosed with an allergic disease according to anamnesis, laboratory results, and skin prick test. H. pylori infection was found in 61.5% of patients with allergic diseases. H.pylori was more frequent in the patients with allergy, unless that difference is not statistically significant (p:0.685, chi –square:0.165)
Conclusion: The prevalence of allergic disorders, including asthma, atopic dermatitis,urticare, and allergic rhinitis has been increasing, and the prevalence of H. pylori infection has been decreasing. In the previous studies, an inverse association has been observed between H. pylori infection and many allergic diseases such as recent wheezing, allergic rhinitis, dermatitis, eczema or rash. In our study, H.pylori was found more frequently unless that difference is not statistically significant (p:0.685, chi –square:0.165).