3062 Associations of Metabolic Syndrome with Asthma and Atopy in Korean Adults

Friday, 16 October 2015
Hall D1 Foyer (Floor 3) (Coex Convention Center)

Ji-Yong Moon, MD , Department of Internal Medicine, Hanyang University College of Medicine, Seoul, South Korea

Sang-Heon Kim, MD , Department of Internal Medicine, Hanyang University College of Medicine, Seoul, South Korea

Ji Young Yhi, MD , Department of Internal Medicine, Hanyang University College of Medicine, Seoul, South Korea

Dong Won Park, MD , Department of Internal Medicine, Hanyang University College of Medicine, Seoul, South Korea

Tae Hyung Kim, MD , Department of Internal Medicine, Hanyang University College of Medicine, Seoul, South Korea

Jang Won Sohn, MD , Department of Internal Medicine, Hanyang University College of Medicine, Seoul, South Korea

Dong Ho Shin, MD , Department of Internal Medicine, Hanyang University College of Medicine, Seoul, South Korea

Ho Joo Yoon, MD , Department of Internal Medicine, Hanyang University College of Medicine, Seoul, South Korea

Background: Whereas obesity is suggested to have a link to asthma, the epidemiological association of metabolic syndrome with asthma have been poorly demonstrated.

Objective: We aimed to explore the relationship of metabolic syndrome with asthma and atopy in Korean adult population.

Methods: Using the data from Korean National Health and Nutrition Examination Survey (KNHANES) in 2010, the study population aged 19 or older were divided into subjects without metabolic syndrome and those with metabolic syndrome that was defined by criteria of the International Diabetic Federation.

Results: The prevalence rates of asthma, determined by self-reported current wheezing, in the subjects without metabolic syndrome and in those with metabolic syndrome were 6.3% and 9.2%, respectively. Multivariate logistic regression analysis adjusting for age, gender and smoking status found that metabolic syndrome was significantly associated with asthma (adjusted OR 1.425, 95% CI 1.040 – 1.952, P = 0.028). There was no significant relationship in metabolic syndrome with atopy, determined by serum levels of the specific IgE to Dermatophagoides farinae, cockroach or dog.

Conclusion: In general population of Korea, subjects with metabolic syndrome have increased risk of asthma.