1000 Anxiety and depression levels in severe asthma patients treated with omalizumab

Wednesday, 14 October 2015
Hall D1 Foyer (Floor 3) (Coex Convention Center)

÷mer ÷zbudak, MD , Department of Respiratory Medicine, Akdeniz University Faculty of Medicine, Antalya, Turkey

Fatih ‹zer, MD , Department of Respiratory Medicine, Akdeniz University Faculty of Medicine, Antalya, Turkey


Asthma, because of  its chronic nature, may adversely affect the life quality of patients leading to mental disturbances. Anxiety and depression can be accure more than on  these patients compared with the healthy population. Life quality survey can be used to evaluate effect of asthma in the terms of physical, psychological and social function on the patients life. In particular, the importance of emotional factors  come to the forefront more  in the case which symptoms can not be controlled. Anxiety is the most common psychological disorders among patients who have  respiratory system disease.  

Materials and methods

We aimed to compare anxiety and depression levels of the patients with severe asthma before  and after  the  omalizumab  treatment. Patients’ anxiety levels were measured with state trait anxiety inventory (STAI) and depression levels were measured with beck depression scale.


Five male (%25), fifteen female (%25) patients enrolled in study. The average age of the patients were 50,25. The average  score of beck depression scale of patients was 25,35 and 8,55 before and after treatment, relatively. The score was higher before treatment, it was statically meaningful when it compared with after treatment scores (p<0.001). The STAI average score was 52,05 before treatment and 42.95 after it. There was a statistically meaningful difference between the anxiety score average before and after the treatment (p<0.0001). The anxiety score was higher before the treatment.

Failure in symptom controlling in asthma can lead to depression. We think that these patients should be examined for psychological disorders. It may improve the quality of life.