Methods: We included 8 patients with symptoms of autoimmune disease, such as autoimmune hypothyroidism, dermatomiositis, systemic vasculitis, autoimmune uveitis, Wegener´s granulomatosis, antiphospholipid syndrome, Kawasaki´s disease and SLE with allergic disease and T and B lymphocytes immunodeficiency. We did the clinical history, skin test and also immunological evaluation with immunoglobulins, IgG subclasses, T lymphocytes absolute numbers and specific antibodies, all of them had diagnosis of allergy, with immunodeficiency and autoimmune disease.
Results: There were included 8 patients, with moderate to severe allergy and recurrent infections, from 3 to 66 years of age, 1 child (12.5%) and 7 adults (87.5%), 7 women (93.3%), 1 men (12.5%). With allergic rhinitis 8 (100%), combination of allergic rhinitis and other allergic disease 2 (25%), asthma 1 (12.5%), atopic dermatitis 1 (12.5%). Also all the 8 patients had humoral, cellular immunodeficiency and autoimmune problems, 7 of them received IVIG therapy on the basis of the immunodeficiency, with evident improvement, 1 did not received and had some improvement of their symptoms.
Conclusions: We found out that the 8 patients with autoimmunity had allergy and also mixed T and B immunodeficiency. We conclude that the physicians should be aware of the correlation in chronic inflammation and the presence of the three immunological clinical problems to give appropriate treatment and improve the prognosis of these patients.