Sunday, 4 December 2011: 13:15 - 00:00
Coral Gallery 3 (Fiesta Americana)
Yanqing Xie, PhD
,
State Key Laboratory of Respiratory Diseases Guangzhou, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical College, Guangzhou, China
Jiaxing Xie, PhD
,
State Key Laboratory of Respiratory Diseases Guangzhou, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical College, Guangzhou, China
Rongquan Huang, MD
,
Guangzhou Medical College, Guangzhou, China
Kefang Lai, Prof.
,
State Key Laboratory of Respiratory Diseases Guangzhou, Guangzhou Institute of Respiratory Disease, The First Affiliated Hospital of Guangzhou Medical College, Guangzhou, China
Nanshan Zhong, MD
,
State Key Laboratory of Respiratory Disease, The First Affiliated Hospital, Guangzhou Medical College, Guangzhou, China
Jing Li, MD
,
State Key Laboratory of Respiratory Disease, The First Affiliated Hospital, Guangzhou Medical College., Guangzhou, China
Background: Upper airway inflammation could be reflected by nasal lavage cytology test, which is characterized by advantages of non-invasive, simple, objective and costless. However, reference values nasal lavage cytology was not established.To establish reference values and positive standard for nasal lavage cytology through screening normal healthy subjects and patients with allergic rhinitis according to strict inclusion criteria.
Methods: To establish reference values and positive standard for nasal lavage cytology through screening normal healthy subjects and patients with allergic rhinitis according to strict inclusion criteria.
Results: There was no statistical significance in gender constitutional proportion, age, height and weight among each group. 95% CI of neutrophils, eosinophils was (0~12.61)/×200 and (0~1.70)/×200, respectively. The median (interquartile range) of neutrophils were 0(0.65)/×200 in AR group, which showed no statistical difference (P>0.05) with that of normal group [0(0)/×200]. A significant difference was found in the median (interquartile range) of eosinophils [6.90(22.40)/×200] in AR group as compared with that of normal control group [0(0.10)/×200, P<0.001].
Conclusions: Establishment of reference values of nasal lavage cytology test is helpful to discriminate normal individuals and patients with allergic rhinitis, but also a non-invasive tool for objective reflection on upper airway inflammation, which is of great value for scientific and clinical purposes.
