Monday, 5 December 2011
Poster Hall (Cancún Center)
Sükran Köse, MD
,
Clinic of Infectious Diseases and Clinical Microbiology, Clinical Allergy and Immunology, Izmir Tepecik Education and Research Hospital, IZMIR, Turkey
Süheyla Serin Senger, MD
,
Clinic of Infectious Diseases and Clinical Microbiology, Clinical Allergy and Immunology, Izmir Tepecik Education and Research Hospital, IZMIR, Turkey
Arzu Didem Yalcin, MD
,
Allergology and Clinical Immunology Unit, Antalya Education and Training Hospital, Antalya, Turkey
Gülsün Cavdar, MD
,
Clinic of Infectious Diseases and Clinical Microbiology, Clinical Allergy and Immunology, Izmir Tepecik Education and Research Hospital, IZMIR, Turkey
Sabri Atalay, MD
,
Clinic of Infectious Diseases and Clinical Microbiology, Clinical Allergy and Immunology, Izmir Tepecik Education and Research Hospital, IZMIR, Turkey
Gürsel Ersan, MD
,
Clinic of Infectious Diseases and Clinical Microbiology, Clinical Allergy and Immunology, Izmir Tepecik Education and Research Hospital, IZMIR, Turkey
Background: Liver disease has been considered a prominent cause of IgE elevation. Significant differences may be observed depending on the cause of liver damage. For viral hepatitis, increased IgE concentrations have been observed during acute hepatitis A and B. Chronic hepatitis B carriers may also have high IgE levels. But no data on serum IgE levels in chronic hepatitis C and hepatitis B patients have been reported. The aim of the study was to evaluate serum IgE levels in patients with chronic hepatitis C and hepatitis B and to corelate with atopic patients.
Methods: Serum IgE levels were determined in 568 adult patients with chronic hepatitis B, in 47 patients with chronic hepatitis C, and 311 patients with atopic diseases.
Results: The averages of serum IgE levels were 103,9 IU/ml in chronic hepatitis C, 95,1 IU/ml in hepatits B patients, and 126,6 IU/ml in atopic patients. There was no statistically significant difference between hepatits B and hepatits C patients. Total serum IgE levels were lower in patients with either chronic hepatitis C or hepatitis B than the atopic group.
Conclusions: According to the results presented, chronic hepatitis C and hepatitis B are not prominent causes of increased serum IgE values. Further studies are needed to clarify the differences and significance of IgE levels between hepatitis and atopic patients.
