Background:
The common variable Immunodeficiency (CVID) is the second cause of primary immunodeficiency. The bronchiectasis are the most frequent structural pulmonary alterations in CVID, which have been principally described in pediatric population, finding the presence of the same ones in 50% of the cases, nevertheless exists inssuficient information about the location and characteristics as type and distribution of the bronchiectasis; in adult population, less information exists still on this matter. High resolution CT scan is valuable for detection of bronchiectasis and may alter treatment of these patients.
Objective
The purpose of this study was to determine the presence of bronchiectasis, their characteristics and most frequent location using a high resolution CT scan in adults whit diagnosis of CVID.
Methods:
This was a cohort study whit 15 adult subjetcs whit the diagnosis of CVID, who underwent a chest high-resolution computed tomography scan, previous signature of a letter of informed consent and with the approval of the committee of ethics and investigation (F-2011-3601-21).
Results:
We studied all the subjects (n=15) whit CVID, finding the presence of bronquiectasias in 73% of the subjects with CVID, 82 % was a women and 8 % males. The most frequent location was in the left lung in 46 % of the cases and 45 bilateral %, with only 9 % of location in right lung. These were more frequent in the low lobe in 42 %, 17 % in top lobe and l6 % diffuse, the rest of them were brought like diffuse, bibasal or parahiliar. In one patient we found the presence of a lefth apical cavitation and only one was brought by presence of pulmonary diffuse fibrosis.
Conclusions:
There was realized a search of bronchiectasis and their characteristics in subjects whit CVID disorders, the incidence of bronchiectasis is higher in our poblation (82%) than in the rest (50% described in other pubiclations). The most affected lung was the left in the lowe lobe. The most frecuente type of bronchiectasis were the cystic form.