4070 Chronic Urticaria and Infections

Wednesday, 7 December 2011
Poster Hall (Cancún Center)

Dr. Nadia Aguilar , Allergy & Clinical Immunology, Specialty Hospital Medical Center XXI Century, Mexico, Mexico City, Mexico

Saul Lugo-Reyes, MD , Allergy & Clinical Immunology, National Institute of Pediatrics, Mexico City, Mexico

Nora Hilda Segura Mendez, MD , Allergy & Clinical Immunology, Specialty Hospital XXI Century National Medical Center, Mexico City, Mexico

Elizabeth Mendieta, Doctors in training , Allergy & Clinical Immunology, Specialty Hospital Medical Center XXI Century, Mexico, Mexico City, Author, Mexico City , Mexico

Background: Chronic Urticaria (CU) is a group of diseases that share a distinct skin reaction pattern. Triggering of urticaria by infections has been discussed for many years but the exact role and pathogenesis of mast cell activation by infectious processes is unclear. The remission of annoying spontaneous chronic urticaria has been reported after successful treatment of persistent infections.

Objective:  To describe the infections found in chronic urticaria patients in our service, by performing a complete medical history, physical examination, laboratory studies and cultures.

Methods: Universe: Consecutive patients with chronic urticaria, with a detailed history, physical examination, laboratory studies underwent clinical viral panel, cultures, biopsy for detection of H. Pylori.

Results: A total of 50 patients, mostly women 82% and 18% men, mean age 41 years. 42% of the total population had salmonella, proteus infection in 20% and 8% brucellosis. Coursed with urinary tract infection 6% of the population. Five patients had positive stool in 3 patients Endolimax nana was isolated and 2 patients reported Giardia lamblia, 5 patients (10%) women had undergone cervicovaginitis two of them infected with S. haemolyticus, the rest was cultivated E. faecalis, and T. Gardenella vaginalis, respectively. Was isolated in two patients and one patient H.pilory HCV infection.

Conclusions: Infections may play a causal role of UC in some cases. Were identified in 42% of cases and gastrointestinal infections by most common cause Salmonellosis. As for genitourinary tract infections, intestinal parasites, Helicobacter pylori, were treated appropriately with antibiotic therapy, found a successful resolution of urticaria mainly in patients infected with Helicobacter pylori. There is growing evidence that persistent infections in chronic urticaria are important triggers, particularly in the case of infection by Helicobacter pylori, so If an infection is identified, it should be appropriately treated and it should be checked whether eradication has been achieved.