2017 The Importance of Recognizing Vocal Cord Dysfunction in the Presence of Allergy and Asthma

Monday, 5 December 2011
Poster Hall (Cancún Center)

Karine Issa-El-Khoury, MD , Allergy and Immunology, McGill University, Montreal Children's Hospital, Montreal, QC, Canada

Jonathan Bayuk, DO , Allergy and Immunology, Hampden County Physician Associates, Northampton, MA

Background: Patients with vocal cord dysfunction (VCD) can often be misdiagnosed with asthma.  This condition is also known as psychogenic stridor, factitious asthma and pseudoasthma, and has been associated with stress, GERD and exposure to irritants. Instead of normal abduction of the true vocal cords during inspiration and adduction during expiration, patients with VCD have inappropriate adduction on inspiration as well as expiration. Symptoms include throat tightness, choking sensation and airway obstruction, and occasionally inspiratory or expiratory stridor.

Methods: An 11-year-old boy with a history of moderate asthma, chronic sinusitis and allergic rhinitis presented to our office for immunotherapy. Months later, he developed paroxystic coughing episodes after which he collapsed from fatigue. Episodes occurred several times during daytime without obvious triggers. There was no respiratory distress, hemoptysis, fever or vomiting. He had already been seen by two pediatric pulmonologists who treated him with steroids for his asthma.

Results: Our pulmonary function tests showed variable extrathoracic obstruction, and laryngoscopy confirmed the diagnosis of VCD. He was started on Tessalon perles, and referred to speech therapy and a psychologist as part of a long-term prevention strategy. Coughing spells have since improved.

Conclusions: Patients with VCD are often diagnosed with asthma and treated with beta-adrenergic agents and inhaled corticosteroids with little improvement. Coughing will cause a brief adduction of the vocal cords followed by abduction when forceful exhalation is produced. Panting can also be beneficial by activating the posterior cricoarytenoid muscle and causing vocal cords abduction. By having purposeful coughing spells, our patient was trying to relieve the discomfort of the adducted vocal cords by forcing them to abduct. This case illustrates that VCD can be a missed diagnosis, which potentially can prolong treatment in patients with pre-existing allergy and asthma.