2142 Urticarial Vasculitis AFTER Bee-STING THERAPY

Monday, 5 December 2011
Poster Hall (Cancún Center)

June-Hyuk Lee , Respiratory and allergy, Soonchunhyang University Bucheon Hospital, Bucheon, South Korea

Sung Woo Park , Division of Respiratory and Allergy Medicine, Soonchunhyang University Hospital, College of Medicine, Bucheon, South Korea

An-Soo Jang , Respiratory and allergy, Soonchunhyang University Bucheon Hospital, Bucheon, South Korea

DoJin Kim , Respiratory and allergy, Soonchunhyang University Bucheon Hospital, Bucheon, South Korea

Choon-Sik Park , Respiratory and allergy, Soonchunhyang University Bucheon Hospital, Bucheon, South Korea

Background: Bee-sting therapy is one of the oriental traditional medical therapy. Some chemical components of bee venom have been known to have anti-inflammatory effects. Recently, traditional therapists use one chemical component (e.g. Apitoxin) for injection therapy using a syringe, instead of sting method with bee itself as to be known traditional method. 31-year-old woman had a lower back pain because of mild HIVD in lumbar spine for 5 months. She had bee-sting therapies for several times for 4 months. During this period, she didn’t have any side effects and pain was improved. Her back pain was recurred 4 weeks ago and had bee-sting therapy again. The traditional doctor performed intramuscular injections of 1 mL of Apitoxin on her lower back muscle. After 4 days, reddish skin lesions and swelling were developed on her legs and spread to trunk. She was transferred and treated with systemic corticosteroid and antihistamine.

Methods: Serum speicific IgE and IgG were measusred by immunoCAP for and skin biopsy perforemed accompaied with managements.

Results: High levels of specific IgG but negative of IgE to honeybee venom were observed by immunoCAP. Skin biopsy was revealed as an urticarial vasculitis. 

Conclusions: We repot the case that suspious to be serum sickness developed after bee-sting therapy.