Presentation: Aspirin Desensitization Treatment : A Case Report (World Allergy Congress)

Monday, 5 December 2011

Poster Hall (Cancún Center)

Mirta Alvarez, MD , Allergology Department, University Hospital Calixto García, Havana City, Cuba

Lludenich Osoria, MD , Cardiology, Calixto García University Hospital, Havana City, Cuba

Mercedes Ronquillo, MD , Allergology Department, University Hospital Calixto García, Havana City, Cuba

Raúl Castro, MD , Allergens, National Center of Bioproducts, Havana City, Cuba

Doguerti Perez , Calixto García University Hospital, Havana City, Cuba

José Rodríguez, MD , Allergology Department, University Hospital Calixto García, Havana City, Cuba

Catalina Irarragorri, MD , Calixto García University Hospital, Havana City, Cuba

Background: Aspirin (ASA) is one of the best known and most widely used drugs in the world. Patients with coronary artery disease require prolonged treatments with this drug, which is denied to those patients with histories of adverse reactions to it. Methods: In a rapid desensitization protocol a patient with a history of ASA-induced urticaria-angioedema was treated with escalating doses of aspirin administered orally every 25 minutes. Results: The patient completed the desensitization protocol in few hours without complications, and currently is able to take 125 mg of ASA per day without adverse reactions. Conclusions: This report describes the first desensitization treatment with aspirin carried out in our hospital. No other case was found in the national bibliography.

2073 Aspirin Desensitization Treatment : A Case Report