Wednesday, 7 December 2011: 15:05 - 15:20
Gran Cancún 2 (Cancún Center)
Hirohisa Saito, MD, PhD
,
National Research Institute for Child Health & Development, Tokyo, Japan
Learning Objectives:
1. Only basophils are naturally expressing IL-4 that can trigger Th2 cell development from naive T cells.
1. Only basophils are naturally expressing IL-4 that can trigger Th2 cell development from naive T cells.
2. In the igE-mediated late phase asthmatic response, basophils but not mast cells are activated. Basophils are accumulated into the lungs of fatal asthmatics.
3. In murine models, basophils are reported to play an important role in IgG-mediated anaphylaxis or in the antigen presentation.