1008 Olfactory Disfunctions in Patients with Chronic Rhinosinusitis

Sunday, 4 December 2011: 13:15 - 00:00
Coral Gallery 3 (Fiesta Americana)

María Victoria Sánchez Vallecillo , Research Centre of Respiratory Medicine - Faculty of Medicine, Catholic University of Cordoba, Córdoba, Argentina

María Emilia Fraire , Otorrinolaringología, Sanatorio Allende, Córdoba. Argentina, Córdoba, Argentina

Carlos E. Baena-Cagnani, M.D. , LIBRA Foundation, Cordoba, Argentina

Mario Zernotti, MD, PHC , Otorrinolaringologia, Sanatorio Allende, Córdoba. Argentina, Córdoba, Argentina

Background:

There are several factors that could produce olfactory dysfunction. The chronic inflammation of the upper air tract, especially allergic rhinitis is mentioned as a trigger factor. The aim of this study is assess the prevalence and identify clinical features associated with olfactory dysfunction in patients with chronic rhinosinusitis.

Methods:

A prospective, analytical and observational study in adult patients (> 18 years) with chronic rhinosinusitis during the period May-October of 2010. We used the CCCRC (Connecticut Chemosensory Clinical Research Center smell test)

Results:

A total of 33 patients were investigated. In the group of patients between 18-39 years, 73% of patients suffer from hyposmia and 18% anosmia; for the group of 40-64 years, 63% with hyposmia and 37% anosmia; patients older than 65 years, 67% hyposmia and 33% with anosmia. In the smokers group the 11% of patient presented hyposmia and 13% anosmia (p<0.05); 5% in both cases had a history of nasal endoscopic surgery. In patients with chronic rhinosinusitis with nasal polyps have 18% with hyposmia and 19% with anosmia (p<0.05). A 20% with allergic rhinitis had hyposmia while anosmia in 22% (p<0.05). Septal deviation patients had 20% of hyposmia (p<0.001) and 12% anosmia. Patients with turbinate hypertrophy had 22% hyposmia (p<0.001) and 13% anosmia while in the group of patients with Asthma , the 4% had hyposmia and 16% anosmia (p<0.001).

Conclusions:

Nasal polyposis, septal deviation, turbinate hypertrophy, smoke, allergic rhinitis and asthma are negative predictors factors of olfactory dysfunction in patients with CRS. A previous endoscopic surgery, age and sex would not intervene in the olfactory loss.