2102 Cross Sectional Study of 1,822 Pediatric Food Allergy Patients

Monday, 5 December 2011
Poster Hall (Cancún Center)

Takatsugu Komata, MD , Department of Pediatrics, Sagamihara National Hospital, Sagamihara, Japan

Miho Hasegawa , Department of Allergy, Sagamihara National Hospital Clinical Research Center for Allergy and Rheumatology, Sagamihara, Japan

Kiyotake Ogura, MD , Department of Pediatrics, Sagamihara National Hospital, Sagamihara, Japan

Katsuhito Iikura, MD , Department of Pediatrics, Sagamihara National Hospital, Sagamihara, Japan

Makiko Goto, MD , Department of Pediatrics, Sagamihara National Hospital, Sagamihara, Japan

Tomohiro Utsunomiya, MD , Department of Pediatrics, Sagamihara National Hospital, Sagamihara, Japan

Sakura Satou, MD , Department of Allergy, Sagamihara National Hospital Clinical Research Center for Allergy and Rheumatology, Sagamihara, Japan

Takanori Imai, MD, PhD , Department of Pediatrics, Sagamihara National Hospital, Sagamihara, Japan

Morimitsu Tomikawa, MD , Department of Pediatrics, Sagamihara National Hospital, Sagamihara, Japan

Akinori Shukuya, MD, PhD , Department of Pediatrics, Sagamihara National Hospital, Sagamihara, Japan

Motohiro Ebisawa, MD, PhD , Department of Allergy, Sagamihara National Hospital Clinical Research Center for Allergy and Rheumatology, Sagamihara, Japan

Background: The aim of this study is to clarify the cross section of pediatric food allergy patients. We investigated the profiles of food allergy (FA) patients seen in our department.

Methods: The number of food allergy patients seen in our department from January to December in 2010 was a total of 1,822 (male: 1207, female: 615, mean age: 5.8±3.8 y). We collected and analyzed the clinical information of these patients from our medical record. We obtained information on the age of FA onset & FA diagnosis, clinical types of FA at the onset, causative food allergens, other allergic complications, and application of oral immunotherapy (OIT).

Results: The average age of FA onset was 8 months, and that of diagnosis was 1 year old, respectively. The most common clinical types of FA at the time of onset were infantile atopic dermatitis (AD) type with food allergy (66.4%) followed by immediate type (30.8%). Food allergens avoided by the patients were the total number of 4,203 items (2.1 items as average). The most common eliminated food was hen's egg (1,245 cases; 29.6%), followed by cow's milk (786 cases; 18.7%), peanut (449 cases; 10.7%), and wheat (407 cases;  9.7%). Food-dependent exercise-induced anaphylaxis (FDEIA) was the total of 18 cases, and the most common causative food for FDEIA was wheat (10 cases) followed by peach (4 cases). One hundred and seventy five cases (9.6%) were   currently receiving OIT. Main causative foods under OIT were hen's egg (63 cases), cow's milk (80 cases), and wheat (30 cases). The average starting age of OIT was 7.1 years old. Regarding complications of allergic diseases other than FA, eleven hundred nineteen (61.4%) had atopic dermatitis, and 541 (29.7%) bronchial asthma.

Conclusions: We were able to clarify the cross section of food allergy patients in our department and to obtain the basic data to follow continuous transition of these patients.